John Libbey Eurotext

MT Cardio

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Systemic vasculitides: classifications and therapeutic strategies. Volume 2, issue 1, Janvier-Février

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Service de médecine interne et CNRS UMR 7087, hôpital La Pitié-Salpêtrière, 83 boulevard de l’Hôpital, 75651 Cedex 13, Paris

Systemic vasculitides constitute a very mixed group of diseases of unknown pathogenesis, characterized by the existence of inflammatory lesions of the vessel wall. These diseases are classified into three groups according to the size of the vessels injured; small, medium and large vessel vasculitis. Substantial advances have been made in recent years in the physiopathology and treatment of the systemic vasculitides. Systemic vasculitides often remain severe diseases and new more targeted therapeutic strategies should be proposed and evaluated by taking into account the prognostic factors of severity which become essential tools their in management.