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Journal de Pharmacie Clinique

Is there a link between information, knowledge, and pharmacological compliance in patients suffering from psychotic disorders? Volume 21, numéro 2, Juin 2002


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Objective: a sociological investigation was made to study knowledge and information about drugs of ambulatory psychotic patients, and to assess their pharmacological compliance rate. Method: survey questionnaire was designed according to sociological survey's rules. In order to promote patients frankness, the investigator was independent of the medical team. We processed the answers of 63 patients (61% men, mean age 40 years ± 27), having presented with psychotic disorders for an average of 10.5 years ± 13, without addictive comorbidity (CIM10). Results: the compliance rate was only 47%. 36.5% say they received drug information, and 83% say they'd like to get more. Moreover, no correlation stands between those informations, and the patient's knowledge. Both the kind of information and the way they are delivered, seem inappropriate. Patients' drugs knowledge level, about "technical" pharmacological properties as well as about "ideological" beliefs on potentiality, is very low. Besides, a significant correlation appears between the ideological drugs knowledge and patients' compliance behaviour. Conclusion: these results demonstrate that convincing psychotic patients to be compliant is mandatory. It also demonstrates that information procedure needs to be extensively structured.