John Libbey Eurotext

Hépato-Gastro & Oncologie Digestive


Liver transplantation for cholangiocarcinoma: which indications for which results? Volume 25, issue 4, Avril 2018


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1 CHU Pontchaillou, Service de chirurgie hépatobiliaire et digestive, 2 rue Henri Le Guilloux 35033 Rennes Cedex 09, France
2 Faculté de Médecine, Université de Rennes 1, Rennes, France
* Tirés à part

Cholangiocarcinoma are rare tumors with poor prognosis. The majority of cases are intrahepatic or perihilar. The rate of resectability is low. Surgical resection is the only potentially curative treatment, with disappointing results (5-year overall and recurrence-free survival of 40% and 20% respectively), which is why liver transplantation has been evaluated in perilhilar and intrahepatic cholangocarcinomas. This mini-review proposes an overview of literature data to better define the place of transplantation in non-resectable peri-hilar cholangiocarcinomas after a rigorous selection of candidates and a neoadjuvant chemoradiotherapy and its interest in some highly selected cases of intrahepatic cholangiocarcinoma occurring in patients with cirrhosis or healthy liver.

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