Groupe Hospitalier Paris Saint-Joseph, 185, rue Raymond Losserand, 75014 Paris
Anoperineal lesions in patients with Crohn's disease (APLOC) are frequent and remain a diagnosis and therapeutic challenge. APLOC can be directly related to Crohn's disease: primary lesions (ulcerations and skin tags) reflect the inflammatory activity of the disease ; and secondary lesions (fistula, abscess, stricture) are also influenced by infectious processes. Physicians should be aware of various other lesions: infectious (mycosis, herpes, condyloma…), inflammatory (psoriasis, Verneuil's disease…), tumoral, dermatologic (maceration dermatitis, eczema…), haemorrhoids, and common anal fissure. Skin biopsy are required for atypical chronic lesion that does not respond to usual treatments (topical corticosteroids, imidazole antifungals, antibiotics).
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