John Libbey Eurotext

Hépato-Gastro & Oncologie Digestive


Metastatic colorectal cancer in elderly: which chemotherapy regimens and targeted therapies? Volume 24, issue 4, Avril 2017


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CHU Pontchaillou,
Université Rennes 1,
service des maladies de l’appareil digestif,
2 rue Henri Le Guilloux 35033 Rennes Cedex 09,
* Tirés à part

Colorectal cancer (CRC) occurs frequently in elderly, whose life expectancy increases, as well as living conditions. The proportion of elderly patients with metastatic CRC is therefore increasing. Being excluded from therapeutic trials since a long time, elderly patients are now the subject of special attention and dedicated studies. The objective of this review is to present results of studies evaluating the efficacy and tolerability of chemotherapy and targeted therapies (antiangiogenic, anti-EGFR antibody essentially) in the treatment of metastatic CRC in the elderly.