Parasites and blood transfusion: causes and consequences Volume 12, issue 2, Mars-Avril 2006

EFS île-de-France, 83-87 rue des Alpes, 94623 Rungis Cedex, EFS Auvergne-Loire, 25 boulevard Pasteur, 42000 Saint-Étienne, EA 3064, Faculté de médecine, université Jean-Monnet, 45 rue Ambroise-Paré, 42000 Saint-Étienne

An important step in the safety system of blood donations is now reached for possible viral infectious diseases. However, infectious agents can across international borders through immigration and travel. Among of these agents, protozoal agents are rife in endemic way in mainly low income countries, and their introduction has resulted of population movements in industrialised countries. Malaria, American trypanosomiasis (Chagas disease) and protozoal tick-borne diseases as babesiosis can be transmitted by cellular blood components. There are few convincing reports of post transfusional leishmaniosis. The leucoreduction have dropped in the impact of transmission of Toxoplasma gondii and Leishmania ; but, at this moment, there do not appear to be any effective methods to eliminate Plasmodia and Babesia in erythrocytes and Trypanosoma cruzi. So, this review deals with the main parasite diseases that are carried by blood products and focused on their geographical distribution, their human cycles, their main clinical aspects, the implemented measures to prevent transfusion transmitted (TT) malaria and TT Chagas disease in European countries, and the available tools for diagnosis.