UAB Epilepsy Center, Departments of Neurology and Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
Hypothalamic hamartomas are often associated to a progressive epileptic encephalopathy. Non‐invasive data indicates that destruction or isolation of the hamartoma may stop seizures. We present data on patients who underwent stereotactic radiofrequency with or without endoscopy. Epilepsy improved in 60% of patients with minimal morbidity. This approach was less succesful in large lesions. These results indicate that this approach should be considered in patients with small\medium lesions.