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Positron emission tomography in epileptogenic hypothalamic hamartomas Volume 5, issue 4, December 2003

Figure 1. MRI findings.
A) Patient No 1 showing a left-sided, intra-hypothalamic hamartoma associated with a subtle hippocampal asymmetry of uncertain significance; B) Patient No 2 showing a large, right-sided extra-hypothalamic hamartoma; C) Patient No 3 showing a right-sided, intra-hypothalamic hamartoma; D) Patient No 4 showing a left-sided, intra-hypothalamic hamartoma; E) and F) Patient No 5 showing a right-sided, intra-hypothalamic hamartoma on both coronal and sagittal T1 sequences.

Figure 2. FDG-PET.
A) Patient No 2 demonstrated right thalamic and, to a lesser extent, right temporo-polar hypometabolism. B) Patient No 3 showed an extensive, right hemispheric hypometabolism, involving the lateral temporal cortex, the orbito-frontal and fronto-polar cortex, the peri-sylvian region, and the mesial and lateral occipital lobe.

Figure 3. FDG-PET. A) Patient No 4 demonstrated left, lateral, temporo-occipital hypometabolism, but also left parietal abnormalities; B) Patient No 5 showed an extensive, right hemispheric hypometabolism, involving the lateral temporal cortex, the TPO junction, and the inferior parietal lobule.