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Epileptic Disorders

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Multinodular and vacuolating neuronal tumour of the cerebrum: a rare neuroimaging incidentaloma or a potentially treatable cause of focal epilepsy? Volume 21, issue 2, April 2019

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Authors
1 Institute for Neurosurgery,
2 Clinic of Neurology,
3 Institute for nuclear medicine, Clinical Center of Serbia, Medical School, University of Belgrade, Belgrade, Serbia
* Correspondence: Aleksandar J. Ristić Clinic of Neurology, Clinical Center of Serbia, Medical School, University of Belgrade, Dr Subotića 6, Belgrade, Serbia
a Authors contributed equally

Multinodular and vacuolating neuronal tumour (MVNT) of the cerebrum is a relatively new, well defined histopathological and neuroradiological entity, in many cases associated with an early adult-onset epilepsy. These lesions have an indolent course and resemble both malformative and neoplastic processes, combining a focal developmental anomaly and a low-grade tumour. Herein, we report a case of a 48-year-old female patient with left temporal lobe epilepsy associated with MVNT. In addition, a comprehensive review of all the previously published cases is provided with a focus on seizure-related cases, surgical treatment, and postoperative outcome.