Epileptic Disorders


Measurement of seizure freedom in adjunctive therapy studies in refractory partial epilepsy: the levetiracetam experience Volume 8, issue 2, June 2006

Figure 1 Summary of methods used in the analysis. iITT = inferential intent-to-treat.

Figure 2 Seizure freedom rates in levetiracetam (LEV)-treated patients based on Method 1 (white bars) and Method 3 (grey bars).Results include both parts of the crossover trial.

Figure 3 Seizure-free rates with add-on levetiracetam for any 6-month or 12-month period during long-term follow-up (Radtke and Bennett, 2000). Data are shown for the intent-to-treat (ITT) population of 1422 patients, the subgroups treated for at least 6 and 12 months, and the subgroup continuing to receive levetiracetam at the cut-off point of follow-up.