John Libbey Eurotext

Giant hypothalamic hamartoma and dacrystic seizures Volume 9, issue 1, March 2007


  • Giant hypothalamic harmatoma and dacrystic seizures


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Pediatric Neurology Unit, Department of Pediatrics, Department of Neurophysiology. University Hospital Reina Sofia, Córdoba, Department of Pediatric Neurosurgery, University Hospital Doce de Octubre, Madrid, Spain

Ictal crying is a rare type of epileptic seizure associated with hypothalamic hamartoma and with other lesions such as tumours, vascular malformations, hippocampal sclerosis, or cerebral infarction. We describe the case of an infant with gelastic, dacrystic and other types of seizures associated with a giant hypothalamic hamartoma, and present a video sequence of dacrystic seizures. Dacrystic episodes presented in clusters at sleep onset, initially in the form of moaning followed by face-flushing that rapidly evolved to crying, associated with a lateral and upper deviation of both eyeballs, along with clonic aspects of the eyelids. After a few seconds, the crying became less intense, she stared, and oro-alimentary automatisms became prominent along with some slow horizontal movements of the eyes and the head. Following surgery, at the age of nine months, the gelastic seizures stopped, but dacrystic seizures persisted. [Published with video sequences]