University of Bologna, Bologna, Italy
Danish Epilepsy Center, Filadelfia / University of Copenhagen, Dianalund, Denmark
Correspondence: Guido Rubboli
Danish Epilepsy Center,
Filadelfia/University of Copenhagen,
Kolonivej 1 - 4293 Dianalund, Denmark
We present some aspects relevant to the definition and diagnosis of Encephalopathy related to Status Epilepticus during slow Sleep (ESES) to further understand the pathophysiological mechanisms in the light of current knowledge and some recent research. Future lines of research in ESES that include investigation of impairment of sleep homeostasis and disruption of age-related plasticity processes in the developmental age are also discussed.