John Libbey Eurotext

A 16-year-old girl with focal seizures and impaired awareness: divergent non-invasive data related to a diffuse epileptogenic network Volume 18, issue 2, June 2016


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1 IRCCS, Institute of Neurological Sciences of Bologna, Child Neurology Unit, Bologna, Italy
2 Department of Neurology and Comprehensive Epilepsy Program, Brain Institute, Nicklaus Children's Hospital, Miami, Florida
3 Departments of Neurological Surgery, Nicklaus Children's Hospital, Miami, Florida
4 Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA
* Correspondence: Michael Duchowny Department of Neurology and the Brain Institute, Miami Children's Hospital, 3200 SW 60th Court, Miami, Florida 33155, USA

We describe a patient with medically refractory focal epilepsy who presented with divergent non-invasive data, with MRI revealing hippocampal sclerosis and EEG indicating involvement of the occipital lobe. A localized corticectomy over the occipital convexity was performed based on intracranial EEG recording. The patient was seizure-free after four years of follow-up. Electroclinical hypotheses and challenges of defining the epileptogenic network are discussed.