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European Journal of Dermatology

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Topical therapy for psoriasis: a promising future. Focus on JAK and phosphodiesterase-4 inhibitors Volume 26, issue 1, January-February 2016

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Authors
1 USF Sete Caminhos - ACeS Gondomar
2 Department of Dermatology, Centro Hospitalar do Porto, Rua D. Manuel II, s/n, 4099-001 Porto, Portugal
3 Unit for Multidisciplinary Research in Biomedicine, Instituto Ciências Biomédicas Abel Salazar, University of Porto, Portugal
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Psoriasis is a common chronic and disabling skin disorder affecting approximately 2% of the population, associated with significant negative impact on the patient's quality of life [1]. Moreover, psoriasis has been associated with several comorbidities, such as psoriatic arthritis and cardiovascular disease [2, 3]. Plaque-type psoriasis is the most common form and is typically characterized by erythematous papules and plaques with a silver scale, usually localized on the elbows, knees, sacrum [...]