John Libbey Eurotext

European Journal of Dermatology

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Pyoderma gangrenosum in the genital area: successful treatment using adalimumab Volume 28, issue 2, March-April 2018

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Authors
Division of Dermatology, Department of Specialistic, Clinical and Experimental Medicine, University of Bologna, Bologna, Italy

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis clinically characterized by erythematous nodules or pustules that tend to evolve into large ulcers with purplish, undermined borders [1], probably due to a dysregulation of the innate immune system. It usually occurs over the lower extremities, however, unusual presentations have been described, such as in the genital region [2].PG has a slight female predominance [2] and is often associated with inflammatory bowel diseases (IBD). For the [...]