John Libbey Eurotext

European Journal of Dermatology


Persistent elevation of serum interleukin-6 and serum amyloid A levels in patients with recessive dystrophic epidermolysis bullosa Volume 27, issue 1, January-February 2017


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1 Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama,
2 Department of Plastic Surgery, Hamamatsu University School of Medicine, Hamamatsu,
3 Department of Pediatrics, Kawasaki Medical School, Kurashiki,
4 Department of Pediatrics, Kurashiki Central Hospital, Kurashiki,
5 Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki,
6 Department of Dermatology, Okayama Citizens’ Hospital, Okayama, Japan

Recessive dystrophic epidermolysis bullosa (RDEB) caused by a mutation of the type VII collagen gene, COL7A1, is a rare and severe form of epidermolysis bullosa (EB), and is characterised by inherently fragile skin and recurrent blister formation which occurs over the entire body within weeks after birth [1]. RDEB patients persistently have widespread skin ulcers and also develop various complications, including oesophageal stricture, infection, pseudosyndactyly, renal failure, cutaneous squamous [...]