European Journal of Dermatology
MENUPathways to inflammation: acne pathophysiology Volume 21, issue 3, May-June 2011
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Department of Dermatology, Cardiff, University School of Medicine, Heath Park CF14 4XN, United Kingdom
- Key words: acne, androgens, cytokines, diet, genetics, inflammation, Propionibacterium acnes, sebaceous glands
- DOI : 10.1684/ejd.2011.1357
- Page(s) : 323-33
- Published in: 2011
Acne vulgaris affects as much as 80% of the adolescent population and persists in approximately 3% of middle-aged adults. Only a percentage of these persons seek medical help, however, acne can cause levels of anxiety and depression akin to a chronic illness. A recurring question from patients who seek help from various healthcare professionals – their pharmacist, family doctor or dermatologist, is “why?” They also ask questions about a possible familial link, the impact of their diet and the association with their hormones. The following review aims to link these factors with the end result – inflammation.