John Libbey Eurotext

European Journal of Dermatology


Melanocyte biology and its implications for the clinician Volume 9, issue 3, April- May 1999


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Department of Dermatology, University Hospital, De Pintelaan 185, 9000 Gent, Belgium.
  • Key words: melanocyte, melanogenesis, melanosome biogenesis, melanoma, vitiligo.
  • Page(s) : 241-51
  • Published in: 1999

Epidermal and follicular melanocytes are neural crest derived cells that are in close contact with surrounding keratinocytes. By producing melanin in specialized organelles, the melanosomes, and transferring it to the keratinocytes, human skin becomes pigmented. Establishment of cultures of human melanocytes and an increasing interest in photo-carcinogenesis/photoaging have led to an explosion of knowledge concerning the biology of melanocytes.