John Libbey Eurotext

European Journal of Dermatology


Indeterminate cell histiocytosis: a case series and review of the literature Volume 27, issue 5, September-October 2017


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Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing 210042, China
a These authors contributed equally

Indeterminate cell histiocytosis (ICH) is characterized by a proliferation of dendritic cells, which are immunophenotypically similar to Langerhans cells (CD1a+/S-100 protein+), but lack Birbeck's granules. We report herein five patients with ICH and review the literature to outline its clinical, morphological, immunophenotypic and therapeutic features.The patients included three females and two males. Their ages ranged from 8 to 53 years. The disease duration ranged from two months to two years [...]