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European Journal of Dermatology

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Diagnosis and comments: Birt-Hogg-Dubé syndrome Volume 10, issue 5, July - August 2000

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  • Page(s) : 407-9
  • Published in: 2000

A 65-year-old Japanese man was referred to our department for evaluation of facial "warts" on May 12, 1998. He stated that the "warts" had been present for the last 30 years, and that they had gradually increased in number. According to the patient, two brothers out of his seven siblings had similar "warts" on the face, but we could not examine them personally. One of the brothers had undergone sigmoidoscopy when four benign colonic polyps were detected. Dermatological examination revealed numerous, smooth, dome-shaped, skin-colored nodules, 2 to 4 mm in diameter (Fig. 1). They were distributed on the face and neck, and over his upper back and upper arm. There was no preference for the central portion of the face. In addition, pedunculated lesions, 2 mm in size, were also present on the neck and in the axilla.