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Catastrophic gangrene caused by heat-insoluble cryoglobulins Volume 21, issue 5, September-October 2011

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Department of Dermatology, Division of Hematology, Shiga University of Medical Science, Setatsukinowa Otsu, Shiga 520-2192, Japan

ejd.2011.1489 Auteur(s) : Noriki Fujimoto1 noriki@belle.shiga-med.ac.jp, Gen Nakanishi1, Masae Shirai1, Norikazu Fujii1, Hitoshi Minamiguchi2, Keiko Hodohara2, Toshihiro Tanaka1 1 Department of Dermatology 2 Division of Hematology, Shiga University of Medical Science, Setatsukinowa Otsu, Shiga 520-2192, Japan Cryoglobulins usually dissolve at 37̊C [1], but some that only dissolve at a higher temperature have been reported. These proteins are called heat-insoluble cryoglobulins [2]. Here, we present [...]