John Libbey Eurotext

European Journal of Dermatology


Angiosarcoma-related pneumohemothorax treated with intrapleural paclitaxel administration and pleurodesis with OK-432 Volume 28, issue 4, July-August 2018


  • Figure 1
1 Department of Dermatology,
2 Department of Thoracic, Cardiovascular and General Surgery, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan

A 75-year-old Japanese man presented with a three-month history of purpura with a bloody crust on his right forehead (figure 1A). Incisional biopsy was performed and showed a vascular-like lesion with atypical cells positive for both CD31 and CD34 (figure 1B-C), suggestive of cutaneous angiosarcoma. The patient received weekly docetaxel therapy associated with radiation therapy. Two months later, he developed docetaxel-induced pneumonia and the chemotherapy regimen was changed to paclitaxel. However, [...]