John Libbey Eurotext

European Journal of Dermatology


A case of CD4+/CD8+ double-positive primary cutaneous anaplastic large cell lymphoma of the lip involving spontaneous regression after biopsy Volume 27, issue 1, January-February 2017


  • Figure 1
Department of Dermatology, Nara Medical University School of Medicine, 840 Shijo, Kashihara, Nara 634-8522, Japan

Primary cutaneous anaplastic large cell lymphoma (C-ALCL) represents one end of the spectrum of primary cutaneous CD30+ lymphoproliferative disorders and has an excellent prognosis. Spontaneous regression occasionally occurs, but relapse is common [1, 2]. We describe a case of C-ALCL of the lip that exhibited the CD4+/CD8+ double-positive phenotype and completely regressed after biopsy examinations. Cases of C-ALCL in which the condition regresses completely without treatment and does not subsequently [...]