Annales de Biologie Clinique
MENUAspect cytologique normal et pathologique du sang chez le nouveau-né et le jeune enfant Volume 64, issue 1, Janvier-Février 2006
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Service d’hématologie biologique, Hôpital Robert Debré (AP-HP), Paris
- Key words: newborn, blood, microscopic analysis, peripheral blood morphological analysis, red blood cells, leukocyte, platelet, lysosomal storage diseases, metabolism inborn error
- Page(s) : 17-36
- Published in: 2006
Morphological alterations of blood cells are observed early in most hereditary disorders. Therefore, the cytological study of the blood cells is a must for the diagnosis of these disorders in neonates and children. Knowledge of the quantitative and qualitative physiological peculiarities of blood cells in neonates is mandatory for an accurate interpretation. In the present article, the main cytological characteristics of blood cells in healthy neonates and infants and their abnormalities associated with hereditary or acquired blood disorders are reviewed.