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Psychoses chroniques, psychotropes et grossesse Volume 81, issue 2, Février 2005

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Schizophrenia, psychotropic medications and pregnancy.The potential risk of exposing the developing infant to medications during pregnancy in schizophrenic patients should be outweigh by the risk posed by untreated maternal illness. Stopping medications during pregnancy potentially places the mother at high risk for relapse. There are low risks with typical neuroleptics, moderate risks with lithium, higher risks with older anticonvulsants such as valproic acid and carbamazepine, and virtually unknown risks with atypical antipsychotics. Best management of this particularly vulnerable group of women, requires close liaison between the obstetrical and the psychiatric teams while maintaining the mother on the lowest dosage possible of the medication.