John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the International League Against Epilepsy

Might the olfactory bulb be an origin of olfactory auras in focal epilepsy? Volume 18, numéro 4, December 2016


(1) Is the olfactory bulb synaptically stable (unchanging; not epileptogenic) or synaptically plastic (continuously changing; potentially epileptogenic) after full postnatal maturation is achieved?

(2) As the only sensory system lacking projection to the thalamus, what are the components of the intrinsic thalamic equivalent of the olfactory bulb and tract?

(3) What cerebral structures have afferent olfactory projections and thus capable of mediating olfactory auras?



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(1) Synaptically plastic, hence potentially epileptogenic.

(2) Axonless granular neurons and periglomerular neurons that form dendro-dendritic synapses, and the multiple nodules comprising the anterior olfactory nucleus.

(3) Entorhinal cortex of parahippocampal gyrus; amygdala; rostral insula.


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