John Libbey Eurotext

Unilateral thalamic lesion mimicking genetic generalized epilepsy Volume 22, numéro 6, December 2020


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1 Department of Neurology,
2 Department of Radiology,
3 Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
* Correspondence: Kathryn A. Davis Hospital of the University of Pennsylvania, 3400 Spruce Street, 3 West Gates Building, Philadelphia, PA, 19104, USA
* These authors contributed equally

A 26-year-old woman presented with absence seizures since age eight, diagnosed as juvenile absence epilepsy. Absence and bilateral tonic-clonic seizures were well-controlled on valproic acid. Examination was normal. EEGshowed 3-Hz generalized spike-and-wave discharges (figure 1). MRI revealed an infiltrative lesion in the left thalamus and dorsal midbrain (figure 2). Advanced imaging suggested a low-grade glial neoplasm. Follow-up imaging showed no progression.     The thalamus plays [...]

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