John Libbey Eurotext

The effect of oral administration of monosodium glutamate on epileptogenesis in infant rats Volume 22, numéro 2, April 2020


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1 Tekirdag Namık Kemal University, School of Medicine, Department of Pharmacology Tekirdag,
2 Marmara University School of Medicine, Department of Pharmacology, Hastane Yolu Street number 5, 34854 Maltepe Istanbul,
3 Koç University School of Medicine Istanbul, Turkey
* Correspondence: Hasan Raci Yananlı Marmara Üniversitesi - Medical School Pharmacology, Maltepe Başıbüyük 34854 Istanbul, 34854 Turkey
a Authors contributed equally


Glutamate is an excitatory neurotransmitter that is widely distributed throughout the brain. An increase in glutamate concentration or sensitivity of glutamate receptors triggers neurodegenerative diseases, epilepsy in particular. Monosodium glutamate is a substance added to foods to enhance flavour. We investigated the effect of monosodium glutamate on epileptogenesis, as well asheight and weight, in rats that were just weaned.