John Libbey Eurotext

Enteral lorazepam is a promising weaning strategy for midazolam-responsive febrile infection-related epilepsy syndrome (FIRES): a case series Article à paraître


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1 Departments of Pediatrics & Pediatric Neurology, Santokba Durlabhji Memorial Hospital, Jaipur, India
2 Department of Pediatric Neurology, Rainbow Children’s Hospital, Secunderabad, India
3 Department of Pediatric Intensive Care Unit, Rainbow Children’s Hospital, Vijayawada, India
4 Pediatric Neurology Unit, Department of Pediatrics, Bharati Vidyapeeth Medical College, Pune, India
* • Correspondence: Vivek Jain Departments of Pediatrics & Pediatric Neurology, Santokba Durlabhji Hospital, and Medical Research Institute, Bhawani Singh Marg, Jaipur, India

Febrile infection-related epilepsy syndrome (FIRES) is a subcategory of new-onset refractory status epileptics (NORSE), characterized by prior febrile infection, between two weeks and 24 hours before the onset of seizures [1]. FIRES is one of the most devastating forms of epilepsies with difficult-to-control seizures in the acute phase, can require prolonged periods of intensive care unit (ICU) stay, and often leads to drug-resistant epilepsy [2, 3].As the pathophysiological mechanism of this entity [...]