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Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial Volume 31, numéro 6, November-December 2021

  • [1] Sibilla S., Godfrey M., Brewer S., Budh-Raja A., Genovese L. An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: scientific background and clinical studies. Open Nutraceuticals J. 2015;8:29-42.
  • [2] Genovese L., Corbo A., Sibilla S. An insight into the changes in skin texture and properties following dietary intervention with a nutricosmeceutical containing a blend of collagen bioactive peptides and antioxidants. Skin Pharmacol Physiol. 2017;30:146-158.
  • [3] Kawada C., Kimura M., Masuda Y., Nomura Y. Orally administered hyaluronan affects skin dryness and epidermal thickening in photoaged hairless mice. Biosci Biotechnol Biochem. 2016;80:1192-1195.
  • [4] Khare N., Khare P., Yadav G. Recent advances in anti-aging – a review. Glob J Pharmacol. 2015;9:267-271.
  • [5] Farage M.A., Miller K.W., Elsner P., Maibach H.I. Intrinsic and extrinsic factors in skin ageing: a review. Int J Cosmet Sci. 2008;30:87-95.
  • [6] Tanaka M., Yamamoto Y., Misawa E. Effects of aloe sterol supplementation on skin elasticity, hydration, and collagen score: a 12-week double-blind, randomized, controlled trial. Skin Pharmacol Physiol. 2016;29:309-317.
  • [7] Göllner I., Voss W., von Hehn U., Kammerer S. Ingestion of an oral hyaluronan solution improves skin hydration, wrinkle reduction, elasticity, and skin roughness: results of a clinical study. JEBCAM. 2017;22:816-823.
  • [8] Liu L., Liu Y., Li J., Du G., Chen J. Microbial production of hyaluronic acid: current state, challenges, and perspectives. Microb cell fact. 2011;10:99.
  • [9] Oe M., Mitsugi K., Odanaka W. Dietary hyaluronic acid migrates into the skin of rats. Sci World J. 2014;2014:378024.
  • [10] Bukhari S.N., Roswandi N.L., Waqas M. Hyaluronic acid, a promising skin rejuvenating biomedicine: a review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects. Int J. Biol Macromol. 2018;120:1682-1695.
  • [11] Litwiniuk M., Krejner A., Speyrer M.S., Gauto A.R., Grzela T. Hyaluronic acid in inflammation and tissue regeneration. Wounds. 2016;28:78-88.
  • [12] D’Agostino A., Stellavato A., Busico T. analysis of the effects on wound healing of high-and low-molecular weight chains of hyaluronan and their hybrid H-HA/L-HA complexes. BMC cell biol. 2015;16:19. In vitro
  • [13] Masi S. The 2.0 Full Spectrum Hyaluronans Technology to improve bioavailability and efficacy performance. Agro Food Ind Hi-Tech. 2020.
  • [14] Oe M., Sakai S., Yoshida H. Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period. Clin Cosmet Investig Dermatol. 2017;10:267.
  • [15] Kawada C., Yoshida T., Yoshida H. Ingestion of hyaluronans (molecular weights 800 k and 300 k) improves dry skin conditions: a randomized, double blind, controlled study. J Clin Biochem Nutr. 201414-81.
  • [16] Kajimoto O., Odanaka W., Sakamoto W., Yoshida K., Takahashi T. Clinical effect of hyaluronic acid diet for dry skin - objective evaluation with microscopic skin surface analyzer. J New Rem & Clin. 2001;50:548-560.
  • [17] Schwartz S.R., Park J. Ingestion of BioCell Collagen, a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs. Clin Interv Aging. 2012;7:267. ®
  • [18] Hisada N., Satsu H., Mori A. Low-molecular-weight hyaluronan permeates through human intestinal Caco-2 cell monolayers the paracellular pathway. Biosci. Biotechnol Biochem. 2008;72:1111-1114. via
  • [19] Kawada C., Yoshida T., Yoshida H. Ingested hyaluronan moisturizes dry skin. Nutr J. 2014;13:70.