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European Journal of Dermatology

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Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial Volume 31, numéro 6, November-December 2021

Figure 1

Skin profilometry: wrinkle depth and volume. Data are expressed as percentage variation with respect to the baseline value. *** p < 0.001 vs T0 and placebo.

Figure 2

Primos 3D images of crow's feet areas of examples-active treated subjects. a.1 and b.1 refer to samples collected at baseline, whilst a.2 and b.2 refer to samples of the same skin surface area collected after 28 days of treatment. Yellow denotes the most elevated zones and blue denotes least ones.

Figure 3

Skin hydration and TEWL. Data are expressed as percentage variation in respect to the baseline value. *** p < 0.001 vs. T0, ** p < 0.01 vs. placebo.

Figure 4

Skin elasticity and skin firmness. Data are expressed as percentage variation in respect to the baseline value. *** p < 0.001 vs. T0, ** p < 0.01 vs. placebo.

Figure 5

Serum levels of hyaluronic acid. Data are reported as mean ± SEM.