John Libbey Eurotext

Tolerability of tiagabine: a prospective open-label study Volume 4, numéro 4, December 2002

Universitätsklinikum Bonn, Klinik für Epileptologie, Sigmund Freud str. 25, D-53105 Bonn, Germany.
  • Page(s) : 257-60
  • Année de parution : 2003

Introduction Tiagabine-HCl is a new antiepileptic drug (AED) with a unique mode of anticonvulsant action. It inhibits the presynaptic re-uptake of gamma-aminobutyric acid (GABA) into neurons and glia [1]. Its anticonvulsant effect in the treatment of partial and secondarily generalised seizures has been demonstrated in several placebocontrolled studies [2]. We report the results of a large prospective openlabel study of tiagabine. [...]