John Libbey Eurotext

Super-refractory status epilepticus in autoimmune encephalitis treated with interleukin-1 receptor antagonist, anakinra Volume 23, numéro 3, June 2021


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Division of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, China
* Correspondence: Howan Leung 9/F Clinical Science Building, Prince of Wales Hospital, Shatin, New Territories, HKSAR, China

Limbic encephalitis was first described in 1960, characterised by a constellation of subacute onset of episodic memory loss, change in mental state and frequent seizures, with a predominant lesion in the medial temporal lobe and hippocampus [1]. Even though autoimmune encephalitis is not as rare as stipulated in the past, clinical experience is still limited and treatment is often challenging. Methylprednisolone, intravenous immunoglobulin and plasma exchange are considered first-line immunotherapy, [...]