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Rational conversion from antiepileptic polytherapy to monotherapy Volume 5, numéro 3, September 2003

Figure 1. Typical conversion to monotherapy study design
Note. A pseudo-placebo arm was employed in most of the studies while a placebo arm was employed in the levetiracetam study.

Figure 2. Placebo-controlled conversion to monotherapy with levetiracetam: Patient disposition
(reproduced with permission from Ben-Menachem
et al., Epilepsia 2000 [22]).