John Libbey Eurotext

Malignant migrating partial seizures in a 4-month-old boy Volume 13, numéro 2, Juin 2011

Department of Neurology, Reinier De Graaf Group, Delft, Department of Child Neurology, Clinical Neurophysiology, University Medical Centre St Radboud, Nijmegen, The Netherlands

Malignant migrating partial seizures in infancy is an epilepsy syndrome characterised by an onset before the age of six months, multifocal seizures and an EEG pattern consisting of seizures which occur independently and sequentially from both hemispheres. The clinical course of a four-month-old boy with this syndrome, illustrated by video material of the seizures and EEG recordings, is described. The possible neurophysiological mechanism of epileptogenic activity alternating or ‘migrating’ from one hemisphere to the other is discussed.