John Libbey Eurotext

Lacosamide-induced symptomatic sinus node dysfunction Volume 23, numéro 5, October 2021

Illustrations

  • Figure 1
Auteurs
1 Department of Neurology, Musashino Red Cross Hospital, 1-26-1, Kyonancho, Musashino-shi, Tokyo 1808610, Japan
2 Department of Cardiology, Musashino Red Cross Hospital, 1-26-1, Kyonancho, Musashino-shi, Tokyo 1808610, Japan
* Correspondence: Shogo Minomo Department of Neurology, Musashino Red Cross Hospital, 1-26-1, Kyonancho, Musashino-shi, Tokyo 1808610, Japan

A 78-year-old, 60-kg man, with a history of chronic renal impairment, paroxysmal atrial fibrillation, bilateral subdural abscesses, and subsequent symptomatic epilepsy, was brought to our hospital due to syncope. He had been started on lacosamide, at 100 mg/day, in addition to levetiracetam, at 1,000 mg/day, for symptomatic epilepsy four weeks earlier, and electrocardiogram (ECG) at that point showed normal sinus rhythm, heart rate of 65 beats/min, and PR interval of 0.16 seconds (figure 1A). The [...]