Epileptic Disorders
MENUMedication-resistant acute focal motor seizures in a child with COVID-19 affecting the CNS Volume 24, numéro 5, October 2022
Auteurs
Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Correspondence:
Reza Azizimalamiri
Department of Pediatric Neurology, Golestan Medical, Educational and Research Centre, Ahvaz Jundishapur University of Medical Sciences, #90, Golestan Blvd., Ahvaz, Iran
- Mots-clés : focal seizures, COVID-19, cerebrospinal fluid, children
- DOI : 10.1684/epd.2022.1461
- Page(s) : 941-6
- Année de parution : 2022
A perfectly healthy preschool girl presented with acute repetitive focal aware motor seizures, while her brain MRI showed a lesion in the left posterior cortex. After a number of investigations, her cerebrospinal fluid PCR was positive for SARS-CoV-2. Despite receiving at least four anti-seizure medications at appropriate dosages, the seizures continued, and just after administering intravenous immunoglobulin, her seizures stopped. This dramatic response to intravenous immunoglobulin may indicate a hypothetical inflammatory process in the patient’s cortex caused by COVID-19.