John Libbey Eurotext

European Journal of Dermatology

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Therapeutic plasma exchange combined with continuous venovenous hemofiltration in a series of pediatric patients with toxic epidermal necrolysis Volume 31, numéro 3, May-June 2021

Illustrations

  • Figure 1
Auteurs
1 Department of Critical Care Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200062, China
2 Institute of Pediatric Critical Care, Shanghai Jiao Tong University, Shanghai 200062, China
3 Department of Obstetrics & Gynecology, Queen Elizabeth II Hospital, Alberta, Canada
4 Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200040, China

Toxic epidermal necrolysis (TEN), characterized by widespread epidermal necrosis of skin and mucosa, is a rare, fulminating, and life-threatening disorder in adults and children [1]. While in adults, non-pharmacological extracorporeal detoxification including plasmapheresis (therapeutic plasmatic exchange, TPE) and/or continuous venovenous hemofiltration (CVVHF) are used with promising results in refractory disease, limited clinical evidence supports the efficacy of these therapies in children [2, 3]. [...]