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European Journal of Dermatology

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Hidradenitis suppurativa associated with a novel NCSTN mutation and concomitant Klippel-Trenaunay syndrome Article à paraître

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Auteurs
1 Department of Dermatology, the Union Hospital, Fujian Medical University, Fuzhou, China
2 Institute of Dermatology, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China
a These authors contributed equally

Hidradenitis suppurativa (HS) is a chronic, recurring inflammatory dermatosis characterized by abscesses, deep-seated nodules, sinus tracts and scarring in flexural areas [1].The condition affects 0.03-4% of the population and is responsible for a very poor quality of life in the most severe patients [2]. The pathogenesis of HS involves mutations in genes encoding for the γ-secretase complex (GS), including PSEN1, NCSTN and PSENEN genes [3]. Klippel-Trenaunay syndrome (KTS) is a congenital disorder [...]