European Journal of Dermatology


Hairless guinea pig skin: anatomical basis for studies of cutaneous biology Volume 10, numéro 5, July - August 2000

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
  • Page(s) : 357-64
  • Année de parution : 2000

The structural characteristics of the glabrous skin of normal laboratory animals such as mice, rats, guinea pigs, rabbits, dogs and non-human primates differ markedly from those of human skin. For example, these species have skin with a thinner epidermis, relatively flat dermal-epidermal junctions devoid of rete ridges [1], a loosely organized dermal structure [2, 3] and a rudimentary dermal vascular system [3]. Consequently, the reactivity [...]