John Libbey Eurotext

European Journal of Dermatology


Corticosteroid-resistant prurigo nodularis: a rare syringotropic variant associated with hypohidrosis Volume 29, numéro 2, March-April 2019


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1 Department of dermatology, Kawasaki Medical School, Kurashiki,
2 Dermatology, Kawasaki General Medical Center, Kawasaki Medical School, Okayama,
3 Department of Dermatology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan

There are no strong theoretical grounds that topical corticosteroids may improve the outcome of prurigo nodularis (PN). Rather, topical corticosteroids may paradoxically induce a new onset of recalcitrant PN or worsen pre-existing quiescent PN. Here, we present four recalcitrant PN cases treated with potent topical corticosteroids, who showed complete or significant regression of lesions after discontinuation of topical corticosteroid therapy combined with a moisturizer as the treatment modality. [...]