John Libbey Eurotext

European Journal of Dermatology


Basal cell carcinoma in a patient with Wiskott-Aldrich syndrome: an immunohistochemical analysis of infiltrating cells around the tumour Volume 30, numéro 4, July-August 2020


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1 Department of Dermatology,
2 Department of Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8510 Japan

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency caused by loss-of-function mutations in the WAS gene. WAS is characterized by thrombocytopenia, recurrent infections and eczema [1]. Although a predisposition to haematological malignancies is well known due to the anti-tumoral immunodeficiency, we are not aware of cases of basal cell carcinoma (BCC) in patients with WAS [2]. We report herein a case of BCC in a patient with WAS. We examined the infiltrating cells around the [...]