John Libbey Eurotext

European Journal of Dermatology


A minimal form of Proteus syndrome presenting with macrodactyly and hand hyperplasia Volume 13, numéro 2, March - April 2003

Institute of Dermatology, Ospedale Clinicizzato SS. Annunziata, Dipartimento di Oncologia e Neuroscienze, Colle dell'Ara, Via Dei Vestini, Chieti Scalo 66013, Italy
  • Page(s) : 196-8
  • Année de parution : 2003

Proteus syndrome was defined in 1979 by Cohen and Hayden and characterized in 1983 by Wiedemann [1-3] as a rare hamartomatous disorder showing a wide range of abnormalities. The clinical manifestations include partial gigantism of the hands or feet, macrodactyly, plantar/palmar hyperplasia, hemangiomas, lipomas, lymphangiomas, varicosities, epidermal and connective tissue nevi, cranial exostoses, macrocephaly and skeletal anomalies [...]