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European Cytokine Network

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Serum levels of transforming growth factor β1 and C-reactive protein as possible markers of intra uterine insemination outcome Volume 29, numéro 4, October-November-December 2018

Illustrations

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Tableaux

Auteurs
Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Health Sciences, Zekai Tahir Burak Health Practice Research Center, Ankara, Turkey
* Correspondence: A. Seval Ozgu-Erdinc, University of Health Sciences, Zekai Tahir Burak Health Practice Research Center, Ankara, Turkey, Talatpasa Bulvari No 128, 06230, Ankara, Turkey
  • Mots-clés : cytokines, intrauterine insemination, pregnancy, immunology, transforming growth factor, C-reactive protein
  • DOI : 10.1684/ecn.2018.0418
  • Page(s) : 121-6
  • Année de parution : 2018

Objective

Maternal immunity is important for the implantation phase, and exaggerated inflammatory responses may reduce the chance of implantation and pregnancy. Transforming growth factor β1 (TGF-β1) plays a role in the modulation of cellular growth, maturation and differentiation, extracellular matrix formation, immunoregulation, and apoptosis. In this study, we aimed to evaluate the changes in serum TGF-β1 and C-reactive protein (CRP) levels in infertile women following intrauterine insemination (IUI) according to the presence of pregnancy.