Annales de Gérontologie


Vitamin D efficacy on fall occurrence in elderly: a literature review Volume 1, numéro 1, Octobre-Novembre-Décembre 2008

CHU hôpital Bellier, 41 rue Curie, 44046 Nantes Cedex

Vitamin D deficit and fall occurrence are frequent in elderly. Beyond the action of vitamin D on the risk of bone fracture, many studies analyzed the benefice of vitamin D supply on the fall risk. After research in the literature data base, 12 interventional randomized studies have been analyzed. Vitamin D supply reduces the fall risk by 40 to 60% in home-living or institutionalized elderly in 7 studies. The 5 negative studies reveal methodological difficulties such as the number of lost to follow-up, the frequency of vitamin D administration, the daily dose, the quality of data collection of falls. Vitamin D action can be explained by its muscular, cognitive or psychic action. A daily dose of at least 800 IU of vitamin D seems to be necessary in order to obtain a benefice. The reduction of the fall risk will be observed mainly in subjects initially having a level of 25(OH)D less than 75 nmol/L.