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Annales de Biologie Clinique

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Délétion 7q22 dans les pathologies myéloides : attention au design des sondes FISH Volume 77, numéro 2, Mars-Avril 2019

Auteurs
Institut universitaire du cancer Toulouse – Oncopole, Toulouse, France
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Partial deletion of the long arm of chromosome 7 [del(7q),7q-] is a highly recurrent chromosomal aberration in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) [1, 2]. In AML, isolated 7q- is assigned to the intermediate genetic prognostic risk group (ELN classification) or the high risk prognostic group (revised MRC classification). In MDS, isolated 7q- is classified into the intermediate cytogenetic prognostic risk group or into the poor risk group if associated with another abnormality [...]