Epileptic Disorders


Post-ictal subtle ptosis ipsilateral to mesial temporal lobe sclerosis Volume 24, numéro 2, April 2022


(1) What is the quintessential pathology and pattern in limbic epilepsy?


(2) Why can postictal ptosis be related to ipsilateral seizure onset in mesial temporal lobe epilepsy?


(3) What is the anatomical and functional relationship based on between the hypothalamus and the amygdala?






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(1) Not only the dentate gyrus but also the CA1 region of the hippocampus present gliosis, atrophy and neuronal loss, namely hippocampal sclerosis. Other areas of the limbic system show changes, such as the thalamus, the entorhinal cortex, and the amygdala.


(2) This could be explained by Müller muscle paresis, secondary to a transient decrease in sympathetic tone, based on the anatomical proximity and functional alteration between the amygdala and the hypothalamus, which may be exacerbated during the postictal state.


(3) The stria terminalis and the amygdalofugal pathways.








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