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Epileptic Disorders

The Educational Journal of the International League Against Epilepsy

Efficacy of lamotrigine in idiopathic generalized epilepsy syndromes:a video-EEG-controlled, open study Volume 1, numéro 3, Septembre 1999

Service de Neurologie, Hôpitaux Universitaires de Strasbourg, BP 426, F-67091 Strasbourg cedex, France.
  • Page(s) : 159-66
  • Année de parution : 2000

During the last few years many new antiepileptic drugs (AED) have been marketed to treat epilepsy refractory to classic AED. Nevertheless, clinical development is principally designed for licensing and not for clinical practice use. So a majority of trials are of little value in terms of treatment choice in a given patient [1]. Lamotrigine (LTG) is licensed in about 80 countries as add-on therapy in severe refractory epilepsy. Placebo-controlled, [...]