Epileptic Disorders


Coregistration of multimodal imaging is associated with favourable two-year seizure outcome after paediatric epilepsy surgery Volume 19, numéro 1, March 2017


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1 The Jane and John Justin Neuroscience Center, Comprehensive Epilepsy Program, Cook Children's Medical Center, Fort Worth, Texas
2 University of North Texas College of Osteopathic Medicine, Fort Worth, Texas, USA
* Correspondence: Michael Scott Perry Comprehensive Epilepsy Center, Cook Children's Medical Center, 1500 Cooper Street, 4th Floor, Fort Worth, TX 76104, USA


Multimodal coregistration uses multiple image datasets coregistered to an anatomical reference (i.e. MRI), allowing multiple studies to be viewed together. Commonly used in intractable epilepsy evaluation and generally accepted to improve localization of the epileptogenic zone, data showing that coregistration improves outcome is lacking. We compared seizure freedom following epilepsy surgery in paediatric patients, evaluated before and after the use of coregistration protocols at our centre, to determine whether this correlated with a change in outcome.