John Libbey Eurotext

European Journal of Dermatology


A case of IgA pemphigus foliaceus with high scores on drug-induced lymphocyte stimulation tests secondary to various drugs Volume 27, numéro 6, November-December 2017


  • Figure 1
1 Department of Dermatology, Faculty of Medicine, Oita University, Hasama, Yufu, 879-5593, Japan
2 Seguchi Dermatology Clinic, Usa, 879-0453, Japan
3 Department of Dermatology, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka 830-0011, Japan
4 Kurume University Institute of Cutaneous Cell Biology, 67 Asahimachi, Kurume, Fukuoka 830-0011, Japan

Intercellular IgA dermatosis (IAD) is a subset of autoimmune bullous disease with anti-keratinocyte cell surface antibodies belonging exclusively to the IgA class. This condition is classified into five subtypes, viz. subcorneal pustular dermatosis (SPD), intraepidermal neutrophilic IgA dermatosis (IEN), IgA pemphigus vulgaris (PV), IgA pemphigus foliaceus (PF), and unclassified IAD [1]. The major target antigens of these subtypes are desmocollin 1 (Dsc 1) [2], unknown non-desmosomal proteins [3], [...]